There is a lot of speculation that the next game will be in San Francisco (if another game actually comes out.)
But, Bethesda always comes up with surprises. I wouldn't be surprised to see a brotherhood of Steel origin game in Chicago.
I doubt the east coast will be in the next game, but choose "other" if you think so.
It would be cool to have a game in Anchorage and parts of Canada.
I just put Hawaii for the lolz
Thoughts?
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Alaska would be pretty fun or Canada. I want a snow wasteland