I'll start
2000: Pokemon Gold
[Edited on 01.13.2010 3:04 PM PST]
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2000 - Diablo II 2001 - Halo 2002 - Metroid Prime 2003 - Knights of the Old Republic 2004 - Half-Life 2 2005 - Resident Evil 4 2006 - Oblivion 2007 - Bioshock 2008 - Metal Gear Solid 4 2009 - Uncharted 2 Not too shabby of a list.