I managed to do this with a Celestial Nighthawk Golden Gun and the new Raid Armor mods. 20% bonus damage from the Gauntlets, another 25% from the Class Item. I think Empowered Rift also amplifies Golden Gun damage. It was a critical hit, and we had 104 stacks of the Force of Will buff.
It took out a big chunk out of Emperor Calus's health bar (about 1/6), it was hilarious to look at.
I really like some of the new Raid Armor mods, I wish they would work outside the Raid. The helmet perk is kind of lackluster though.
Have you tried them yet? Your opinions?
EDIT: picture link in case the above image doesn't work: https://i.imgur.com/sFVZtkS.jpg
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Someone needs to nerf this guy.