I'm gonna say Vader. Seeing as he has displayed the ability for force choke from literally lightyears away and doesn't even need to be in their presence to kill them. Not to mention he can stop any projectile damage and deflect any laser effects. It's also possible he has access to force lightning which would account for his human speed. And he can literally just tell Goku to kneel before him using the force mind trick and win thst way. Sorry but Spidey stands no chance unless he is on his A game and I mean stronger than he's ever been.